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Patients who are less than 18 years old Pregnant or breastfeeding mothers BMI of 25 or lower Patients with hypersensitivity to semaglutide Patients with a history of pancreatitis, medullary thyroid carcinoma, or endocrine neoplasia syndrome Each patient reacts to weight loss medications differently

Representative sources include peer-reviewed publications indexed by PubMed and scientific literature describing Epitalon, telomere biology, telomerase activity, cellular aging, and longevity research

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Data availability Nucleotide sequences of codon-optimized genes can be found in Supplementary Table 6

Melphalan-induced DNA damage in vitro as a predictor for clinical outcome in multiple myeloma